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Here’s what you need to know
If your medication changes from a brand to a generic, you may have some questions.
Generic medications have been available for many years. Now, a generic version of your specialty medication may be available. Let's talk about what this means for you.
Some specialty medications are available as generics.
Generics contain the same active ingredients and work the same way as the brand-name medication.
After a brand-name medication's patent expires, other manufacturers may seek FDA approval to make a generic equivalent.
They must meet the same FDA standards for safety and quality.
Sometimes, your prescription benefits plan may cover a generic instead of a brand-name medication.
In some cases, the brand may not be covered, or you may need to try the generic first.
Changes can also happen when your plan updates its coverage or new treatment options become available.
Depending on your coverage, some generics may be a lower-cost option.
If your medication changes, your CVS Specialty CareTeam will be there to help guide you through the transition.
Our CareTeam works with your plan and provider to coordinate your prescription, including a switch to a generic if needed.
We'll help you understand your coverage, answer questions and connect you to third-party financial assistance programs.
If you have questions, your CVS Specialty CareTeam is here to help with live chat and 24/7 on-call support.
Generics are medications made with the same active ingredients as brand-name drugs. You may already be taking one. Like the brand-name medication, generics are FDA-approved*, and:
- Contain the same active ingredient, strength and dosage
- Deliver the same expected therapy results
- Meet the same safety and high-quality standards
Some generics are also specialty medications. These may require extra support, monitoring or coordination with your CareTeam to treat complex or long-term conditions.
Why do medications change?
Your medication may change to a generic because your prescription benefit plan covers it instead of the brand-name medication. This can happen if:
- A new generic may now be available and may require a change
- The brand is not covered or requires trying the generic first
- Your prescription benefit plan updates its coverage
- State law requires you to change to a generic medication
- Generics may offer a lower-cost option depending on your coverage
What stays the same?
Generics are designed to provide the same treatment as your brand-name medication:
- The same active ingredient, strength and dose
- Taken the same way (for example, by mouth)
- Works the same way to treat your condition
- Meets the same FDA-reviewed standards for safety, quality and effectiveness
The color or shape may be different, but that won’t affect how it works. If you notice side effects from any drug, talk with your pharmacist or provider.
Support for starting a generic medication
Have a question about your medication or treatment? Your CVS Specialty CareTeam is here to help whenever you need support. Common questions include how to take medications, side effects or symptoms, drug interactions and insurance or billing concerns.
Getting your medications should be as easy as possible. Refill your medication online, in the app or by phone — at a time that works for you. Plus, you can sign up for text or email reminders* to stay on track.
Your CVS Specialty CareTeam can help connect you to:
- Manufacturer assistance programs
- Nonprofit or charitable foundations
- Other third‑party financial assistance and social needs resources
If approved, assistance may be available for a limited time and may require you to reapply.*
Reach out to your CVS Specialty CareTeam. We're here to help with any questions you have. Our dedicated team is available from 8 AM to 9 PM ET Monday to Friday and 9 AM to 6 PM ET Saturday to Sunday.
About specialty generics
A specialty generic medication is a generic version of a brand-name specialty medication. Like other specialty medications, it may require special handling, storage, monitoring or safety precautions. Some are taken by mouth, while others are given by injection or infusion. Because of these special needs, they are often managed through a specialty pharmacy.
A specialty generic medication works the same way as the brand-name medication. It contains the same active ingredient and has the same strength, dosage, safety, quality and expected results. It must meet the same U.S. Food and Drug Administration (FDA) standards as the brand-name medication.
Not all specialty medications have a generic option. A generic version may become available after the brand-name medication's patent expires.
Specialty generic medications can vary in color, shape, size or packaging. They contain the same active ingredient as the brand-name drug. But some inactive ingredients, such as dyes, preservatives or fillers, may differ. These differences do not affect how the medication works. If you have allergies or notice side effects, talk with your pharmacist or provider.
Specialty generic medications meet the same FDA standards for safety, quality and effectiveness as brand-name drugs. They work the same way and provide the same clinical benefit.
Specialty generic medications may cost less because manufacturers don't have to repeat the research and clinical studies done for the brand-name medication. Competition among manufacturers can also help keep costs down.
Many people save money with specialty generics, but your out-of-pocket cost depends on your prescription benefits plan. Your CVS Specialty CareTeam can help you compare costs and understand your options. Get more information about financial assistance support.
Some specialty generics are available only through specialty pharmacies or require special monitoring programs. Specialty pharmacies help ensure proper handling, patient education and ongoing support.
As a CVS Specialty patient, you can get your specialty generics and other medication delivered to your home or office. You can also pick them up at any local CVS Pharmacy®* nationwide. Learn more about your delivery and pick up options.
Yes. Your CVS Specialty CareTeam can help with medication education, coverage and approval questions, transitioning to a generic medication, refills and treatment-related support. Chat live with your CareTeam.
Specialty generics are FDA‑approved versions of brand‑name drugs made from chemicals (often pills or capsules). Biosimilars are also FDA-approved, highly similar versions of biologic medications, both made from living cells. To learn more about biosimilars, visit our Biosimilars Patient Education Center.
You can learn more about specialty generics by visiting the Generic Drugs Patient Education Center at the FDA website for additional information.
What you need to know
Sometimes, your prescription benefit plan may cover a generic instead of a brand-name medication. In some cases, the brand may not be covered at all, or you may need to try the generic first before the prescription benefit plan will approve the brand.
These changes are a normal part of prescription coverage and can happen when new treatment options become available or when your prescription benefit plan updates its coverage. Coverage updates can vary by prescription benefit plan and timing. This means you may see changes sooner than others or may have different coverage for the same medication depending on your prescription benefit plan.
For some patients, generics may also offer a lower-cost option, depending on your coverage. When more than one generic is available, costs may be lower.
Your provider plays an important role in deciding if a generic medication is right for you. In many cases, your pharmacy and prescription benefit plan may also be involved.
Changes are usually based on your prescription benefit plan or state requirements. If a change happens, your provider will review your treatment and help determine what’s appropriate for your care.
It’s completely understandable to want to stay on a medication that’s working well. Generic medications are designed to provide the same clinical benefit as the brand-name version. If you have concerns, you should always talk with your provider before making any changes.
What may change is the medication’s name, appearance or packaging.
Depending on your prescription benefit plan, your cost or coverage may also change. Your CVS Specialty CareTeam can walk you through any differences, so you feel prepared before you start your new medication.
It depends. In some cases, your provider may write a prescription specifically for a generic medication. In other cases, your pharmacy may be able to dispense an FDA‑approved generic version of your medication based on your prescription and prescription benefit plan. Your pharmacy or provider can tell you if you need to do anything.
It depends on your prescription benefit plan. Some generic medications may be covered under an existing prior authorization, while others may require a new one. If your medication needs a prior authorization, your provider will work with your pharmacy and prescription benefit plan to handle this process for you. Contact your prescription benefit plan for more details.
Yes. If your prescription benefit plan makes a change, you may receive notice before the change happens. Your pharmacy may also contact your provider if you need a new prescription. If you have questions about a medication change, your pharmacist or provider can talk to you about what to expect.
If you are new to a specialty pharmacy, your CVS Specialty CareTeam will help guide you through next steps. This may include:
- Reviewing your prescription and insurance coverage
- Setting up medication delivery or pickup
- Explaining how to store and take your medication correctly
- Connecting you to available support and resources
Our CareTeam is available to answer questions and provide ongoing support. You can also visit Getting started with CVS Specialty for more information.
Financial assistance
It depends. Many generic medications cost less than brand‑name medications, but your out‑of‑pocket cost depends on:
- Your prescription benefit plan
- Which medications are covered
- Any available financial assistance programs
Your CVS Specialty CareTeam can help explain how your coverage applies.
It depends. Some generic medications may have manufacturer or third‑party assistance programs available. Availability and eligibility vary by medication, insurance type and program rules. Reach out to your CVS Specialty CareTeam to explore available options.
Yes. Your CVS Specialty CareTeam can help connect you to:
- Manufacturer assistance programs
- Nonprofit or charitable foundations
- Other third‑party financial assistance and social needs resources
If approved, assistance may be available for a limited time and may require you to reapply. For more information, visit our financial assistance page.
Yes. Some nonprofit organizations and patient advocacy groups offer support for eligible patients, including help with out‑of‑pocket costs for medications. Availability depends on your condition, medication and funding status.
Your CVS Specialty CareTeam can help identify resources that may be available to you.
Prescription benefit plans vary. Some plans apply assistance programs toward your deductible or out‑of‑pocket maximum, while others may not.
It’s important to understand how your specific plan works. For questions about your coverage, contact your prescription benefit plan or speak with your CVS Specialty CareTeam.
Additional medication support
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Steps to get started
New to specialty medications? Understand what happens next, how your CareTeam supports you and find answers to common questions.
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Condition resources
Explore the condition education center to discover articles, videos and inspiring stories from other patients with your specialty condition.
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More about generics
The FDA provides comprehensive information on generic medications, featuring patient education materials, answers to common questions and safety overviews.
FDA (U.S. Food and Drug Administration).
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*FOR GENERICS SOURCE: U.S. Food and Drug Administration. Generic Drugs: Overview & Basics. Available at: https://www.fda.gov/drugs/generic-drugs/overview-basics Accessed August 19, 2026.
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*FOR SIGN UP FOR TEXT OR EMAIL REMINDERS: Patients receive real-time prescription status updates only after providing consent to CVS Specialty. Patients can register online and use our mobile app once the patient has received their first medication shipment. Patients can pre-register at cvs.co/specialty-digital if they haven’t received their first medication shipment.
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*FOR FINANCIAL ASSISTANCE PROGRAM INFORMATION: Patients approved for third-party assistance may qualify for support for a limited period of time or up to a maximum benefit amount, depending on program requirements. Patients may need to reapply periodically. Eligibility criteria and funding availability vary by program, foundation and payor requirements.
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FOR MEDICATION AND PICK-UP OPTIONS: Specialty delivery options are available where allowed by law. In-store pick up is currently not available in Oklahoma. Puerto Rico requires first-fill prescriptions to be transmitted directly to the dispensing specialty pharmacy. Products are dispensed by CVS Specialty and certain services are only accessed by calling CVS Specialty directly. Certain specialty medication may not qualify. Services are also available at Long’s Drugs locations.
This information is not a substitute for medical advice or treatment. Talk to your doctor or health care provider about your medical condition and prior to starting any new treatment. CVS Specialty assumes no liability whatsoever for the information provided or for any diagnosis or treatment made as a result, nor is it responsible for the reliability of the content.
CVS Specialty does not operate all the websites/organizations listed here, nor is it responsible for the availability or reliability of their content. These listings do not imply or constitute endorsement, sponsorship, or recommendation by CVS Specialty.